Frequently Asked Questions: What is the difference between Aleve PM & Advil PM?

The active ingredients in Advil PM include ibuprofen, an NSAID, and diphenhydramine, a gentle, non-habit forming sleep-aid. The active ingredients in Aleve PM include naproxen, also an NSAID, and diphenhydramine. Both of these medications include a nonsteroidal anti-inflammatory drug (NSAID) for pain relief in addition to a sleep aid. The difference between these products is the active ingredient (the NSAID), which determines the dosing in the product.