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The active ingredients in Advil PM include ibuprofen, an NSAID, and diphenhydramine, a gentle, non-habit forming sleep-aid. The active ingredients in Aleve PM include naproxen, also an NSAID, and diphenhydramine. Both of these medications include a nonsteroidal anti-inflammatory drug (NSAID) for pain relief in addition to a sleep aid. The difference between these products is the active ingredient (the NSAID), which determines the dosing in the product.
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†Based on 7 hours of sleep which is the minimum recommended amount
††Among leading OTC nighttime pain relievers. Among those with a preference in a nationwide test.
*Among OTC pain relievers.
**Among OTC brands.
>Based on OTC sales.
‡‡Among OTC pain and sleep medications. Based on a survey of doctors.
^Among branded OTC nighttime pain relievers.